CGP 3466B maleate

CAS No. 200189-97-5

CGP 3466B maleate ( Omigapil (Maleate); Omigapil maleate )

Catalog No. M27464 CAS No. 200189-97-5

Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 Get Quote
5MG 66 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
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Biological Information

  • Product Name
    CGP 3466B maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
  • Description
    Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).(In Vivo):Treatment with Omigapil (0.1 mg/kg) in 12-week-old dyW/ mag mice results in improved muscle regeneration and increased force .
  • Synonyms
    Omigapil (Maleate); Omigapil maleate
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    200189-97-5
  • Formula Weight
    391.4
  • Molecular Formula
    C23H21NO5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=C\C(O)=O)\C(O)=O.C(N(CC#C)C)C=1C=2C(OC=3C(C1)=CC=CC3)=CC=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ríos F, et al. Anaerobic digestion of amine-oxide-based surfactants: biodegradation kinetics and inhibitory effects. Biodegradation. 2017 Aug;28(4):303-312.
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